Single Cell Analysis Market Assessment, Size, Value, Share, Growth, Trends, Consumer Analysis, Competition, Industry Analysis, Actionable Insights Report; By Product Type, By Cell Type, By Technique, By Workflow, By Application, By End-User, By Region and Country; Outlook and Forecasts, 2024 – 2030

Report Summary

The Global Single Cell Analysis Market reached USD 3.6 billion in 2023 and is projected to grow to USD 10 billion by 2030, reflecting a robust CAGR of 15% from 2024 to 2030. This significant growth is driven by expanding applications in disease diagnosis, drug discovery, and development. Advancements in sequencing technology, innovations in single-cell analysis and cell isolation techniques, and the increasing occurrence of cancer also fuel market expansion. This new research study provides a comprehensive analysis of industry trends, pricing dynamics, patent activity, KOL insights, and value chain analysis. The report provides an in-depth assessment of market size, value, share, and growth trends, accompanied by detailed consumer analysis and a competitive landscape. It also offers actionable insights and forecasts for the period 2024 to 2030.

What is Single Cell Analysis?

Single Cell Analysis is the precise examination of individual cells to uncover their diverse characteristics and functions. Integrating genomics, transcriptomics, proteomics, and metabolomics, SCA offers researchers a comprehensive understanding of cellular behavior, essential for exploring disease mechanisms, developmental processes, and therapeutic responses. This sophisticated analytical approach enables researchers to scrutinize cells at the molecular level, revealing hidden variations within apparently uniform cell populations. These insights provide pivotal understanding of cellular functions, differentiation pathways, and disease progression. 

Single-cell analysis spans a range of critical applications in specialized fields. In Oncology, it serves to distinguish specific subgroups within cancer cells, unravel the mechanisms behind drug resistance, and tailor therapies personalized to individual patients. Neuroscience utilizes this technology to delve into the complexities of neuronal development, function, and the underlying dysfunctions observed in neurological disorders. Immunology benefits from single cell analysis by meticulously characterizing diverse immune cell types and their intricate roles in immune responses and autoimmune conditions, providing deeper insights into immune system dynamics. In Drug Discovery, researchers leverage single cell analysis to pinpoint novel targets for drug development and to assess drug effectiveness at a cellular level, enhancing precision in therapeutic approaches. Meanwhile, in Stem Cell Research, the technology aids in deciphering the differentiation pathways of stem cells and exploring potential therapeutic uses in regenerative medicine.

Single Cell Analysis Market Growth Trends

There is a rising demand for personalized medicine, fueled by the need for customized treatments based on individual cellular characteristics. Additionally, increased government funding in cell biology and related fields supports research advancements. Technological progress has led to more accessible and user-friendly single cell analysis tools, with integration of AI and machine learning enhancing data analysis capabilities. The incorporation of Omics technologies including genomics, transcriptomics, proteomics, and metabolomics at the single-cell level has significantly expanded the scope of applications in understanding complex biological systems and diseases. 

The single cell analysis market has also broadened its reach across oncology, immunology, neurology, and stem cell research fields. In addition, the pharmaceutical and biotechnology sectors are progressively integrating single cell analysis into their strategies for drug discovery and development. Collaborative efforts among academic institutions, biotech firms, and healthcare providers are on the rise, fostering innovation. Progress in bioinformatics tools and data analysis algorithms further supports the handling, processing, and interpretation of extensive single-cell datasets, enabling profound insights into cellular function and heterogeneity. 

Single Cell Analysis Technology Advancements

Single Cell Analysis encompasses a diverse array of techniques designed to scrutinize individual cells in intricate detail. Next-Generation Sequencing (NGS) enhances genomic analysis by significantly improving accuracy and throughput. Mass Cytometry facilitates advanced protein analysis at a single-cell resolution, while Microfluidics optimizes the isolation and handling of individual cells. High-Resolution Imaging employs cutting-edge microscopy to provide detailed observations of cellular structures.

Advancements in single cell analysis technology have brought about significant developments. Multi-omics Platforms integrate RNA, proteins, and metabolites analysis within a single cell, offering a comprehensive view of cellular activity beyond gene expression alone. Next-Generation Sequencing (NGS) has made notable progress with increased throughput capabilities, enabling simultaneous sequencing of thousands of single cells. Advancements in error correction algorithms and sequencing chemistry have enhanced the accuracy of single-cell RNA sequencing (scRNA-seq), while ongoing refinements have made high-throughput single-cell sequencing more cost-effective.

Microfluidic technologies have greatly improved single-cell isolation efficiency, reducing sample loss and contamination. These advancements have integrated microfluidics with other technologies such as NGS and mass spectrometry, enabling combined genomic, transcriptomic, and proteomic analyses. Robust platforms such as Drop-seq and Seq-Well are now instrumental for high-throughput single-cell RNA-seq, while microfluidic-based organ-on-chip models provide controlled environments for studying single-cell behavior.

In High-Resolution Imaging, techniques such as Super-Resolution Microscopy (STORM, PALM) enable nanometer-level visualization of cellular structures, complemented by advancements in Live-Cell Imaging that allow real-time observation of cellular processes. Machine Learning and Big Data Analytics play crucial roles in managing complex single-cell datasets. Tools such as Cell Ranger and Seurat utilize machine learning algorithms to effectively analyze and visualize single-cell data, aiding in extracting insights, identifying cellular patterns, and predicting cell behavior. Cloud-based platforms further support collaborative research by offering storage, sharing, and analysis capabilities for single-cell data.

CRISPR-Cas9 technology has revolutionized gene editing by enabling targeted manipulation within individual cells, supporting studies on gene function, disease model development, and potential applications in personalized medicine. Recent innovations include high-throughput CRISPR screens at the single-cell level and the use of CRISPR activation (CRISPRa) and interference (CRISPRi) for gene regulation studies. 

Spatial Transcriptomics is an emerging technology that maps gene expression patterns across entire tissues, revealing intricate cellular interactions within complex biological environments. Single-Cell Proteomics delves into protein expression at the single-cell level, providing deeper insights into cellular function and heterogeneity. Furthermore, advances in mass spectrometry techniques are broadening access to single-cell proteomics, revolutionizing the study of protein expression at a cellular level. Single-Cell ATAC-seq (Assay for Transposase-Accessible Chromatin sequencing) allows the study of chromatin accessibility at the single-cell level, shedding light on gene regulation mechanisms within individual cells. Optimized protocols and computational tools have improved the analysis and interpretation of single-cell ATAC-seq data, enhancing its utility in genomic research.

Single Cell Analysis Market Actionable Insights

• In clinical diagnostics, there is a notable rise in using single cell analysis for early disease detection and personalized treatment strategies, enhancing patient outcomes. 

• Within cancer research, SCA is extensively applied to unravel tumor heterogeneity and advance targeted therapies, driving innovations in oncological treatments.

• Tailoring solutions to specific research domains and disease types is becoming crucial, reflecting a strategic focus on specialized applications of single-cell technologies.

• Increasing regulatory clearances for SCA-based diagnostics and treatments highlight growing acceptance and regulatory support.

• The development of robust bioinformatics tools is pivotal for managing and interpreting intricate single-cell data, enhancing operational efficiency and insight generation across research and clinical applications.

• Efforts to automate and integrate data analysis processes aim to streamline workflows, boosting efficiency and data quality in single-cell analysis.

• There is a concerted effort to enhance accessibility and affordability of single-cell analysis tools, making them more widely available to diverse research communities.

• Collaborations with pharmaceutical and biotech companies are key, driving innovation in single-cell analysis tools tailored for drug discovery and personalized medicine applications.

Single Cell Analysis Market Regulatory Landscape

In the U.S., the Single Cell Analysis industry operates within rigorous regulatory frameworks aimed at ensuring product safety, efficacy, and quality. Key regulations include those enforced by the FDA (Food and Drug Administration). High-risk single-cell analysis devices intended for diagnostics require Premarket Approval (PMA), necessitating submission of comprehensive scientific and clinical data to demonstrate safety and effectiveness. Moderate-risk devices may undergo 510(k) clearance, showing substantial equivalence to legally marketed devices. Laboratories performing single-cell analysis, particularly for diagnostics, must adhere to Clinical Laboratory Improvement Amendments (CLIA) regulations, ensuring standards for personnel qualifications, quality control, and proficiency testing. Good Laboratory Practice (GLP) guidelines govern research and development, maintaining integrity and reliability in non-clinical laboratory studies.

For projects funded by NIH (National Institutes of Health) grants, adherence to specific guidelines on research integrity, data management, and ethical conduct is mandatory. Data privacy and security are crucial under the Health Insurance Portability and Accountability Act (HIPAA), applying when handling identifiable health information from single-cell analysis. Compliance entails rigorous protocols ensuring data security, patient privacy, and authorization for research use. In California, the California Consumer Privacy Act (CCPA) and California Privacy Rights Act (CPRA) grant residents rights over personal data, including access, deletion, and opting out of sale, influencing operational practices nationwide.

In Europe, regulatory oversight is governed by CE Marking and the In Vitro Diagnostic Regulation (IVDR). Single-cell analysis devices intended for diagnostics must conform to IVDR standards, involving rigorous clinical evaluation for performance, safety, and clinical benefits. CE marking certifies compliance with essential safety, health, and environmental requirements for European markets, requiring manufacturers to undergo conformity assessment procedures. Compliance with the General Data Protection Regulation (GDPR) is mandatory for handling personal data derived from single-cell analysis, safeguarding genomic and phenotypic data through stringent data protection measures and rights for data subjects. Clinical trials involving single-cell analysis in Europe must comply with the EU Clinical Trials Directive and Regulation, emphasizing ethical conduct and regulatory oversight through Good Clinical Practice (GCP) guidelines.

Regulatory oversight across the Asia Pacific region varies significantly by country, influencing market entry strategies and operational frameworks for single cell analysis industry. In China, approval from the National Medical Products Administration (NMPA) is mandatory, involving rigorous testing and clinical trial requirements. Japan's Pharmaceuticals and Medical Devices Agency (PMDA) enforces pre-market approval and GCP compliance for clinical trials. India's Central Drugs Standard Control Organization (CDSCO) regulates safety, efficacy, and clinical trial approvals. Australia's Therapeutic Goods Administration (TGA) mandates listing or registration for market approval, while South Korea's Ministry of Food and Drug Safety (MFDS) oversees market approval and clinical trial conduct.

What are the Growth Drivers, Challenges, and Opportunities in Single Cell Analysis Market?

Cutting-Edge Technologies Fueling Single Cell Analysis Market Expansion

Advancements in single cell technologies are advancing robust growth in global single cell analysis market. Continuous technological progress is not only propelling the field forward but also enabling significant breakthroughs. These innovations are enhancing accessibility for researchers and expanding the single cell analysis market horizons. Key technological advancements such as next-generation sequencing (NGS), mass cytometry (CyTOF), and microfluidics have transformed single-cell analysis. These technologies offer superior resolution, heightened sensitivity, and multiplexing capabilities, facilitating detailed examination of individual cells. Moreover, integrating omics technologies such as genomics, transcriptomics, proteomics, and metabolomics at the single-cell level has broadened the application spectrum of single cell analysis, enabling deeper insights into complex biological systems and diseases. Advances in microfluidics have streamlined workflows, accelerating cell manipulation and analysis processes. Furthermore, progress in bioinformatics tools and data analysis algorithms supports the efficient handling, processing, and interpretation of large-scale single-cell datasets, enhancing understanding of cellular function and heterogeneity. Additionally, CRISPR-Cas9 technology permits precise gene manipulation within single cells, facilitating studies on gene function and the development of therapeutic interventions. 

Research Funding Impacts Growth in Single Cell Analysis Market

Increased research funding from government agencies and private foundations is driving significant growth in the global single cell analysis market. This surge in funding, particularly directed towards disciplines such as cell biology, neuroscience, immunology, and related fields, is propelling the expansion of single cell analysis technologies. In academia, this financial support is fostering extensive growth, empowering universities and research institutions to utilize single cell analysis for foundational research and innovative applications. Within biomedical research, single cell analysis plays a pivotal role in advancing basic research, facilitating drug discovery, and supporting development efforts. Researchers leverage this technology to explore cellular heterogeneity, identify biomarkers, and elucidate disease mechanisms at the cellular level, enhancing our understanding of complex biological processes. The adoption of single cell analysis in clinical diagnostics is experiencing significant growth, particularly in oncology. It is increasingly utilized for analyzing tumor heterogeneity, detecting minimal residual disease, and advancing personalized medicine approaches. Beyond oncology, its applications extend into fields such as immunology, neurology, and infectious diseases, where it holds promise for transforming diagnostic and therapeutic practices. As ongoing research continues to unveil new applications and benefits of single cell analysis across diverse fields, the single cell analysis market is poised for further expansion.

Impact of Single Cell Analysis in Advancing Precision Medicine

The increasing demand for personalized medicine underscores the critical role of single-cell analysis in comprehending disease heterogeneity within tumors and diseased tissues. This understanding is pivotal for developing precisely targeted therapies. Through the analysis of molecular profiles of individual cancer cells, researchers can pinpoint potential drug targets and devise personalized treatment strategies that promise enhanced efficacy and reduced side effects. Furthermore, monitoring how individual cells react to treatment, enables adaptive therapeutic approaches that optimize patient outcomes. The rise in precision medicine initiatives and investments in personalized medicine research is amplifying the demand for single cell analysis technologies. These initiatives aim to propel the advancement of personalized therapies tailored to individual cellular profiles, thereby stimulating further expansion within the single cell analysis market. 

Single Cell Analysis Drives Innovation in Regenerative Medicine

Regenerative medicine offers substantial growth prospects, bolstered by single cell analysis capabilities. This technology plays a pivotal role in optimizing and characterizing cell therapies, including those involving stem cells, through precise identification and selection of cells with specific properties and functions. As regenerative medicine progresses, the integration of single cell analysis is poised to expand significantly, promising innovative advancements in therapeutic strategies. Furthermore, collaboration between biopharmaceutical firms and technology providers is enhancing single cell analysis market prospects. These partnerships focus on integrating single cell analysis into drug discovery and development processes, aiming at applications such as target identification, drug screening, and biomarker discovery.

User-Friendly Workflows and Cost Reduction Key to Single Cell Analysis Market Growth

User-friendly workflows and cost reduction strategies are pivotal in overcoming current challenges within the single cell analysis industry. Despite existing hurdles such as high costs and complex workflows associated with single cell analysis tools, these obstacles present significant opportunities for market expansion. Streamlining the analysis process through intuitive automation interfaces will broaden adoption among researchers without specialized expertise. Moreover, initiatives aimed at lowering instruments and consumables costs will enhance affordability, thereby fostering wider adoption across research and clinical environments. Standardizing protocols will play a crucial role in ensuring data quality and reproducibility, further bolstering the attractiveness and adoption rates of single cell analysis technologies.

What are the Single Cell Analysis Market Segmentations and Bifurcations? 

Single Cell Analysis Market Segmentation, By Product Type

• Consumables
  • Reagents
  • Assay Kits
  • Beads
  • Microplates
• Instruments
  • Microscopes
  • Hemocytometers
  • Flow Cytometers
  • NGS Systems
  • PCR Systems
  • High-Content Screening (HCS) Systems
  • Cell Microarrays
  • Automated Cell Counters
  • Others Instruments

On the basis of product type, global single cell analysis market is categorized as instruments and consumables. In 2023, consumables dominated single-cell analysis market, driven by their frequent replenishment compared to instruments, which are typically a one-time investment. This segment's prominence is further bolstered by its vital role in genetic research, exosome analysis, and RNA and DNA isolation, all of which require specific consumables tailored to different analysis methods and target molecules.

The consumables segment continues to lead due to ongoing advancements in assay kits and reagents, enhancing workflow efficiency and data quality across various applications. Several factors contribute to the consumables segment's substantial market share, including widespread adoption of isolation products, frequent purchases of buffers, reagents, and cell sorting beads. 

Revenue generation in the instruments segment primarily stems from new installations, replacements of outdated equipment, and associated service offerings. Meanwhile, the instruments segment shows promising growth prospects, fueled by increasing demand for high-throughput and automated platforms for single-cell analysis. Automated instruments are anticipated to experience significant growth in the coming years, leveraging advanced features and sophisticated analytical capabilities to meet evolving market demands.

Single Cell Analysis Market Segmentation, By Cell Type

• Animal Cells
• Microbial Cells
• Human Cells

The global single cell analysis market is bifurcated by cell type into human cells, animal cells, and microbial cells. Analysis and research in animal cells focus on individual cells across various species, primarily used in biomedical research, drug development, and veterinary diagnostics. There is a noticeable trend towards deeper insights into cellular heterogeneity and disease mechanisms, driving demand for specialized tools tailored to enhance animal cell analysis.

Microbial cell analysis includes bacteria, fungi, and other microorganisms, applied extensively in environmental studies, industrial biotechnology, and healthcare. This segment plays critical roles in bioprocessing to optimize microbial strains for industrial applications such as biofuel production, environmental monitoring to assess microbial communities in diverse environments, and infectious disease research directing on microbial pathogenesis and antibiotic resistance mechanisms. Advances in metagenomics and single-cell genomics are expanding applications in agriculture, bioremediation, and microbial bioprocessing.

Human cell analysis covers primary cells, stem cells, and cancer cells, indispensable in clinical diagnostics, regenerative medicine, and personalized therapy. Key applications include cancer research for profiling tumor heterogeneity and identifying therapeutic targets, cell therapy to ensure quality control and monitoring of therapeutic cell products, and neuroscience studies examining neuronal circuits and brain cell interactions. Trends in single-cell transcriptomics and spatial profiling are advancing precision medicine, alongside growing interest in immune cell profiling and therapeutic cell engineering.

Single Cell Analysis Market Segmentation, By Technique

• Flow Cytometry
• Next-Generation Sequencing
• Polymerase Chain Reaction
• Microscopy
• Mass Spectrometry
• Other Techniques

The single cell analysis market incorporates essential techniques including flow cytometry, next generation sequencing (NGS), polymerase chain reaction (PCR), microscopy, mass spectrometry, and other innovative technologies. Flow cytometry evaluates cells based on size, granularity, and fluorescence intensity, widely utilized in immunology, oncology, and infectious diseases. NGS performs DNA and RNA sequencing at the single-cell level, crucial for genomic research and disease diagnostics. PCR amplifies DNA sequences within cells, playing a key role in gene expression analysis and pathogen detection.

Microscopy techniques such as confocal and electron microscopy offer intricate visualization of cellular structures, supporting advancements in biology and neuroscience. Mass spectrometry identifies molecules within cells, facilitating studies in proteomics and drug monitoring. Emerging techniques such as microfluidics for automated workflows, single cell electrophysiology, spatial transcriptomics, imaging mass cytometry, and CRISPR-Cas9 for precise gene editing are driving innovations across diverse scientific disciplines with specialized applications.

Single Cell Analysis Market Segmentation, By Workflow

• Single Cell Isolation & Library Preparation
• Downstream Analysis
• Data Analysis

On the basis of workflow, single cell analysis market is categorized into downstream analysis, data analysis, and single cell isolation & library preparation. In 2023, single cell isolation & library preparation segment held significant revenue share, driven by a diverse array of applications within single cell analysis (SCA). This sector experienced heightened demand for products facilitating cell isolation and library preparation, encompassing essential kits and specialized reagents. Industry leaders offered a range of solutions for single-cell isolation, including FACS and MACS systems for handling heterogeneous cell suspensions, microdissection techniques for fixed tissue samples, as well as advanced technologies such as flow cytometry and microfluidics, all contributing to revenue growth.

The downstream analysis segment is poised for rapid expansion, stimulated by recent technological advancements. Key technologies such as next-generation sequencing for cellular expression analysis, mass spectrometry, and Fluorescence in situ hybridization (FISH) have emerged as pivotal tools in SCA workflows. Additionally, there is a notable trend towards automation and the integration of artificial intelligence for enhanced data analysis capabilities. The market has seen the development and adoption of scalable software solutions and computational methods known for their adaptability and high success rates. The increasing availability and use of database tools underscore the rising accessibility and interest in SCA technologies across various scientific applications.

Single Cell Analysis Market Segmentation, By Application

• Oncology     
• Immunology
• Neurology
• Stem Cell
• Non-Invasive Prenatal Diagnosis
• In-Vitro Fertilization (IVF)
• Others

In 2023, oncology segment stood as the leading application segment in the single cell analysis market, capturing over 30% market share. Single cell analysis has proven indispensable in diagnosing cancer cells, offering precise identification of genetic variations, cell proliferation states, mutation frequencies, and cell types. This capability underscores its pivotal role in advancing cancer diagnosis and treatment, driving significant market growth. 

The immunology segment is poised for the fastest growth during the forecast period. Single cell analysis techniques facilitate detailed characterization of immune cell populations, enabling researchers to delve into gene expression profiles, epigenetic modifications, and protein expressions at a single-cell resolution. Such insights are crucial for understanding molecular mechanisms governing immune cell behaviors, including T-cell lineage commitment and B-cell maturation. Moreover, these techniques are instrumental in studying immune responses to diverse stimuli, ranging from pathogens and vaccines to cancer cells.

Currently, single cell analysis is predominantly utilized for research purposes rather than medical applications. However, escalating demand for stem cell therapies in regenerative and personalized medicine is a key driver of market expansion. Research applications are projected to experience considerable growth during the forecast period, buoyed by advancements in single cell technologies.

Single Cell Analysis Market Segmentation, By End-User

• Research and Academic Laboratories
• Biotechnology & Pharmaceutical Companies
• Hospitals & Diagnostic Laboratories
• Others

In 2023, academic and research laboratories held a substantial share of more than 70% in the single cell analysis market based on end-user segmentation. This dominance underscores the extensive adoption of single cell analysis (SCA) technology within research environments. Numerous ongoing scientific projects at universities worldwide utilize SCA techniques extensively, contributing significantly to its adoption. The integration of spatial genomics has further bolstered single cell analysis in research activities, enhancing the capabilities of academic and research laboratories. Additionally, the development of new tools aimed at overcoming research constraints continues to stimulate market growth.

The biotechnology and pharmaceutical companies segment is poised for significant expansion. Technological advancements, such as the application of microfluidics in cell and gene therapy development, have driven the uptake of SCA among biotechnology and pharmaceutical firms. Moreover, the increasing integration of multi-omics techniques in drug development and research is anticipated to further propel market growth in this segment.

What are the Regional and Country Trends in Single Cell Analysis Market? 

Global Dietary Supplements Market - Regional Insights and Trends 

• North America
• Europe
• Asia Pacific
• Middle East & Africa
• South America

The global single cell analysis market is segmented across North America, Europe, Asia Pacific, South America, and Middle East & Africa. In 2023, North America led the global single cell analysis market in terms of market share, followed by Europe and Asia Pacific markets. Several factors contribute to North America's dominance, including robust research infrastructure, substantial investments in research and development, the presence of key industry players, multiple government funding initiatives, heightened awareness of personal healthcare expenditures, rapid adoption of innovative analytical tools, and a well-trained workforce. The U.S. notably drives much of the growth within North America single cell analysis market.

Asia Pacific is projected to witness the fastest CAGR in the single cell analysis market during the forecast period. This growth is fueled by the rapid expansion of the pharmaceutical and medical industries, a growing elderly population, increasing incidences of cancer, advancements in healthcare infrastructure, and rising government initiatives. Additionally, the prevalence of chronic diseases across the region is expected to further boost market demand. The influx of foreign investments into the market is driven by the region's growing burden of infectious diseases. Governments in Asia Pacific are actively supporting research through funding for research institutes and offering tax incentives to biotechnology and life sciences companies, thereby contributing to the escalating demand for single cell analysis technologies to support these endeavors.

Single Cell Analysis Market Report: Scope & Snapshot

Single Cell Analysis Industry - Competition Dynamics

The global single cell analysis market is fiercely competitive, with key players such as 10x Genomics, Agilent Technologies, Apogee Flow Systems, Becton, Dickinson & Company (BD), BGI, bioMérieux, Bio-Rad Laboratories, Corning Incorporated, Cytek Biosciences, Danaher Corporation, DiaSorin, Fluidigm (Standard BioTools), Fluxion Biosciences, Illumina, Menarini Silicon Biosystems, Merck, NanoCellect Biomedical, Novogene, On-chip Biotechnologies, Oxford Nanopore Technologies, Promega Corporation, QIAGEN, RareCyte, Sartorius, Takara Bio, Tecan Group, Thermo Fisher Scientific, and others.

To solidify their market positions and expand product and service outreach, key industry players are implementing various strategic initiatives, including expansion activities and partnerships. The market is distinguished by significant innovation, driven primarily by technological advancements. The rising demand for advanced analytical tools in innovative research, coupled with substantial funding, has led to the development of high-throughput equipment characterized by automation, high sensitivity, and accuracy. These features are crucial for the effective analysis of scarce samples. Additionally, increasing R&D investments by key companies present substantial growth opportunities for the industry, further fueling its expansion.

Single Cell Analysis Industry Developments

• In February 2024, Takara Bio introduced two cutting-edge single-cell solutions: the Shasta Total RNA-Seq Kit and the Shasta Whole-Genome Amplification Kit, marking a significant enhancement to the company’s product line.

• In February 2024, 10x Genomics, Inc. expanded its single-cell technology portfolio with the launch of GEM-X. This new offering includes Chromium Single Cell Gene Expression 3'v4 and Chromium Single Cell Immune Profiling 5'v3 assays, reinforcing 10X Genomics' position in the market.

• In February 2024, Singleron Biotechnologies unveiled new laboratories in Ann Arbor, Michigan. These state-of-the-art facilities will provide a comprehensive range of single-cell analysis services, from tissue dissociation to single-cell multi-omic analysis, along with automation instruments and bioinformatics support.

• In January 2024, Singleron Biotechnologies debuted the AccuraSCOPE Single Cell Transcriptome and Genome Library Kit at the Festival of Genomics in the UK. This innovative kit allows researchers to simultaneously profile the full genome and full-length transcriptome, offering a powerful tool for diverse research applications. 

• In January 2024, BD company unveiled a collaboration with Hamilton Ink, a robotics developer, with the goal of developing automated solutions for single-cell multiomics research. This partnership is set to enhance efficiency and accuracy in data collection processes.

• In September 2023, Illumina, Inc. partnered with Singleron Biotechnologies to develop an optimized workflow that automatically initiates DRAGEN single-cell RNA sequencing analysis following the sequencing of a Singleron GEXSCOPE single-cell library using an Illumina NextSeq 2000 system.

• In August 2023, Lightcast Discovery availed USD 49 million in Series B financing to advance its single-cell platform for functional analysis, accelerating product development and company growth. 

• In August 2023, BioSkryb Genomics, Inc. partnered with Research Instruments to distribute BioSkryb’s ResolveDNA® and ResolveOME™ single-cell amplification tools throughout Singapore and Southeast Asia, thereby expanding the company’s market reach.

• In June 2023, Honeycomb Biotechnologies, in collaboration with Revvity, launched new solutions to advance single-cell research. These innovations aim to push the boundaries of what is possible in the field.

• In May 2023, BD Company announced the BD FACSDiscover S8 Cell Sorter. This cutting-edge instrument incorporates breakthrough technologies enabling researchers to reveal previously unseen cellular details in traditional flow cytometry experiments.

• In April 2023, Fluidigm Corporation (now Standard BioTools Inc.) launched the Hyperion XTi Imaging System. This system provides high-precision imaging and quantification of complex biological information at the single-cell level, representing a significant advancement in imaging technology.

• In June 2022, Merck partnered with Agilent Technologies to advance Process Analytical Technologies (PAT), crucial for real-time release and Bioprocessing 4.0, enhancing bioprocessing workflow efficiency and reliability. 

• In March 2022, Mission Bio launched the Tapestri Solution specifically designed for Solid Tumor Research. This comprehensive single-cell DNA sequencing workflow encompasses a protocol for nuclei isolation preparation, pre-designed research panels tailored for breast cancer and glioblastoma multiforme, and an advanced single-cell copy number variation (CNV) bioinformatics tool. These elements collectively offer researchers robust tools for conducting in-depth studies.

• In August 2021, Danaher Corporation completed its acquisition of Aldevron, which now operates independently within Danaher's Life Sciences segment, continuing to drive innovation in the field.